Mitf protein atlas
Web1 jan. 2024 · To clarify the molecular mechanism underlying Nrf3-mediated melanogenesis in response to Fsk, we investigated the effect of Nrf3 overexpression on Mitf gene expression, which encodes a master regulator of melanogenesis. 17 Mitf mRNA and protein levels were elevated in Fsk-treated oeNrf3 cells in comparison to Fsk-treated … http://genome.cse.ucsc.edu/cgi-bin/hgGene?hgsid=1604921059_rVn1WbQrVVz6m7V7RtaRB8ojEueA&hgg_section_method_close=1
Mitf protein atlas
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WebRabbit polyclonal MITF antibody. 100% Bioguaranteed. US EN. Applications Products Services Support. All Photos (3) SAB4501879. Anti-MITF antibody ... Prestige Antibodies ® Powered by Atlas Antibodies, affinity isolated antibody, buffered ... Anti-MITF Antibody detects endogenous levels of total MITF protein. MITF (microphthalmia-associated ... WebMITF. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. …
WebAtlas. Tissue i. The Tissue section contains information regarding the expression profile of human gene both on the mRNA and protein level. The protein expression data from 44 … WebCell atlas. Showing subcellular location of MITF (bHLHe32, MI, WS2, WS2A). We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Webmedicinal, diagnostic or therapeutic use. No products from Atlas Antibodies may be resold, modified for resale or used to manufacture commercial products without prior written approval from Atlas Antibodies AB Rev. December 2012 Atlas Antibodies AB Phone +46(0)8 54 59 58 50 IBAN SE91 6000 0000 0004 6991 6761 Bankgiro 5469-1092 WebAntibody information for antibodies HPA003259 and CAB002578 used in analysis of ENSG00000187098 / MITF. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. ... In atlas . …
WebNormal Function. The MITF gene provides instructions for making a protein called melanocyte inducing transcription factor. This protein plays a role in the development, survival, and function of certain types of cells. To carry out this role, the protein attaches to specific areas of DNA and helps control the activity of particular genes.
Web16 jan. 2024 · In melanocytes, cAMP activates protein kinase A (PKA), which phosphorylates and activates the cAMP response element-binding protein (CREB). CREB is a component of a transcription factor complex that drives transcription of microphthalmia-associated transcription factor (MITF), which is known as the master regulator of … chad chenotWebInvitrogen Anti-MiTF Monoclonal (D5), Catalog # MA5-14154. Tested in Immunohistochemistry (Paraffin) (IHC (P)) and Gel Shift (GS) ... (86%) showed MITF expression. Scale bar, 50 mum. (D) Immunoblot analysis of MITF in total protein lysates from 3 normal kidneys and 3 kidney angiomyolipoma tumors. (E) H3K27ac ChIP-seq … chad chen dancerWebWe show that BRAF induces MITF transcription through the MEK/ERK cascade and the transcription factor BRN2. Thus, we propose that oncogenic BRAF down-regulates the MITF protein by targeting it for degradation in an ERK-dependent manner, but then counters this by stimulating MITF transcription in a BRN2-dependent manner. hanpo fried foodWebSummary of MITF expression in human tissue. Nuclear expression mainly in melanocytes. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. Don't show this again. Search: han port wattmeterWebWaardenburg Syndrome Type 2A. Tassabehji et al. (1994) demonstrated mutations in the MITF gene in affected individuals in 2 families segregating Waardenburg syndrome type 2A (WS2A; 193510).Both mutations affected splice sites in the MITF gene. One might expect that the MITF mutations would result in abnormal proteins which, when combined with … chad cheneyWeb6 jul. 2016 · Objective: This study investigated the role and mechanism of action of G protein-coupled estrogen receptor (GPER) in melanogenesis. Methods: GPER expression was detected in the A375 human melanoma cell line and B16 mouse melanoma cell line. Cell proliferation, melanin content, tyrosinase (TYR) activity, cyclic adenosine … chad chen attorneyWeb3 aug. 2015 · Because of the demand on lysosomal function by mitophagy, we investigated a role for the transcription factor EB (TFEB), a master regulator of lysosomal biogenesis, in this process. We show that during mitophagy TFEB translocates to the nucleus and displays transcriptional activity in a PINK1- and Parkin-dependent manner. chad chenoweth